In some individuals, taking just a small amount more than the recommended total daily dose
of acetaminophen (4 grams per day) may lead to liver injury. Acetaminophen has a narrow
safety margin. This means that there is little difference between the maximum recommended daily
dose and a potentially harmful dose. There is scientific agreement that taking a large amount of
acetaminophen over a short period of time causes liver injury, but there are varying views on the
specific threshold dose for toxicity.[/b]